1964 is a year in the 20th century.
- January 22: Samantha T. Mulder is born in Chilmark, Massachusetts to William and Teena Mulder. (TXF: "Conduit")
- February 22: Future FBI Special Agent Dana Katherine Scully is born in Annapolis, Maryland to William and Margaret Scully. (TXF: "Paper Clip")
- Alfred Fellig registers with the New York City Police Department as a crime scene photographer for the first time. This is the first time he uses the name "Alfred Fellig." (TXF: "Tithonus")
- On his "Furthur" bus, Ken Kesey tells Melvin Frohike all Humans have a third eye, and if it were opened it we would "see a new reality, one closer to God." (TXF: "Via Negativa")