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1965 is a year in the 20th century.
- February 10: Some type of insect casing is discovered near Heuvalman's Lake in Georgia (TXF: "Quagmire").
- Future Detective Kelly Ryan is born (TXF: "Soft Light").
- Fake death of Unit 731's commander Doctor Takeo Ishimaru, later known as Shiro Zama (TXF: "Nisei").