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Eugene Openshaw (played by Nick Tate) was a medical doctor who worked for the Syndicate. He held a Nobel Prize in genetics.

While operating on Cassandra Spender in a train car in the Potomac Yard outside of Washington, D.C., he and his team was attacked by a group of faceless aliens. Openshaw was the only survivor, aside from Cassandra – who was deliberately allowed to live so that the Project would be revealed and thus destroyed. While in a hyperbaric chamber in a hospital, Openshaw was visited by the Cigarette Smoking Man and he informed him that Cassandra was a successful hybrid. He told the CSM that "a man should never live to see his children or his work destroyed." Apologizing to his colleague, the CSM adjusted the controls for the chamber, killing Openshaw. (TXF: "Two Fathers")

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