Melissa and Dana were two very different people. Melissa believed in new age mysticism, whereas Dana was a firm believer in hard science. Melissa came to see Dana when she had returned to the hospital after her abduction and claimed she could feel Dana's spirit was still inside her body.
After Scully discovered the implant placed in her neck, it was Melissa who suggested her to undertake regression therapy in an attempt to uncover the truth about her abduction. (TXF: "The Blessing Way")
As Melissa lay dying in hospital, Scully asked for Albert Hosteen to go and pray for her ailing sister, (TXF: "Paper Clip") as he had done for Fox Mulder shortly before. (TXF: "The Blessing Way") However, Melissa soon passed away.
Some time after Melissa's death, Scully began to receive mysterious phonecalls from someone sounding mysteriously like her. (TXF: "Christmas Carol") After discovering Emily Sim, Scully is at first under the impression that the young girl is Melissa's daughter, before discovering that she is in fact Scully's own child.
|"Mulder? Where are you?"|
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|Members of the Scully family|
| William Scully · Margaret Scully · William Scully, Jr. · Melissa Scully |
Dana Scully · Charles Scully ·Tara Scully · Matthew Scully · William Scully III