With the X-files closed, Mulder is contacted by a political ally and sent on a dangerous mission to a radio telescope in Arecibo, Puerto Rico.

While continuing work not related to the X-files, Mulder apparently finds evidence of a giant worm-like monster in the New Jersey sewage system.

Apparently prompted by messages from digital appliances with instructions to kill, several residents of a small farming community suddenly turn violent and dangerous.

A new partner joins Mulder as he investigates the deaths of several victims who were killed by apparently nonexistent forces.

Mulder becomes involved in a hostage situation with an escaped psychiatric patient who claims to be terrified of frequent alien abductions. (Part 1 of 2)

Mulder attempts to search for Scully when she is abducted by Duane Barry, the escaped mental patient who recently held Mulder hostage. (Part 2 of 2)

With Scully missing, Mulder closes in on an "Unholy Trinity" of vampiresque killers and finds himself falling for a mysterious woman who is the prime suspect.

Scully miraculously appears in a Washington DC hospital, unknowingly supervised by a nurse who may never have existed.

When a moving shadow appears on a video transmission from a volcano, a volcanologist asks Mulder and Scully to investigate the incident.

The agents investigate a suggested link between a religious cult of vegetarians and the abduction of several teenagers, although they find that the disappearances are actually connected to a deadly event in their own past.

Mulder and Scully uncover strange occurrences in an old-age care home when one of the nurses is attacked by an unseen force she claims to be one of the residents, a 74 year old man.

When a detective mysteriously uncovers the remains of an FBI agent who disappeared in the 1940s while investigating a murder case similar to a modern-day one she is investigating, Mulder and Scully believe that the original killer had passed his genetic trait of violence to his grandchild.

A mortuary worker who collects hair and fingernails from dead bodies begins to kill people to expand his collection, and he sets his sights on Scully.

After a teenager is ritualistically murdered in a small town, Mulder and Scully are caught up in a secret occult practice within the local PTA and a substitute teacher with odd powers.

After several murders occur within a Haitian refugee camp, Mulder and Scully are caught in the middle of a secret battle involving a Voodoo priest and the camp commander.

After four identical men are killed and their obituaries are e-mailed to Mulder, a mysterious CIA agent informs him and Scully that the killer is a bounty hunter sent to destroy the start of a colony of clones. Meanwhile, Mulder is distracted when his sister, Samantha, suddenly returns. (Part 1 of 2)

Mulder and his sister race to evade the alien bounty hunter and uncover more of the insidious conspiracy. (Part 2 of 2)

Strange things happen in a zoo that result in several deaths, including a government employee and apparently an invisible elephant.

In the North Atlantic, Mulder and Scully investigate the crew of a US Navy Ship, all of whom somehow radically aged. The agents locate the ship but, like the vessel's crew before them, Mulder and Scully also suffer from rapid aging.

A bizarre murder in Florida brings Mulder and Scully to a town populated by circus freaks and sideshows performers of all shapes and sizes, bringing into question the very definition of "normal."

With Scully's help, Mulder investigates a strange death that he believes may be an example of poltergeist activity.

After several men in a prison die of a mysterious illness, Scully tries to discover the cause while Mulder attempts to find two escapees who could potentially spread the disease.

Mulder and Scully encounter a man who is afraid of his own shadow.

Mulder and Scully investigate the disappearance of man in a town where the residents really are what they eat.

A computer hacker discovers evidence against the Syndicate that is so damning that its revelation to the public would be nothing short of catastrophic, leading Mulder into a race against sinister agents to learn the truth. (Part 1 of 3)